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Nutrition 216 — at a Glance
| Course: | Antioxidants in Health and Disease II · 2 PACE-approved CE hours |
| Faculty: | Howard Benedikt, DC, DCBCN · Clinical Nutrition Faculty, CCEDseminars |
| Format: | On-demand online video with assessment · downloadable handouts · instant certificate |
| Pricing: | $20/hr · automatic 10% off at 6–9 hrs, 20% off at 10+ hrs in one order · no promo codes |
| Approval: | PACE Provider #34015544 · co-sponsored by Texas Chiropractic College · acceptance varies by state |
Board-approved · PACE Provider #34015544 · CE Broker auto-reporting for states served · Instant certificate
Reactive oxygen species are not just damage — they are signals that regulate gene expression, inflammation, repair and apoptosis, and the line between therapeutic and harmful antioxidant dosing runs straight through that signaling. Nutrition 216 is the advanced continuation of the Antioxidants series: how ROS drive gene expression, how disease-specific antioxidant protocols are constructed, and where indiscriminate supplementation crosses into harm.
Dr. Howard Benedikt takes free-radical pathology beyond the introductory concepts — antioxidants in health and in disease, the advanced ROS signaling pathways of cell physiology, the epigenetic implications of ROS and your genes, and the therapeutic targets that follow — then translates it into patient management: evidence-based antioxidant interventions for the care plan, diet versus supplementation decisions for the individual patient, and the safe usage thresholds that protect immune function, cellular repair and the adaptive response to exercise.
Choose Your Nutrition Path — Three Lanes, One Curriculum
The Nutrition library — sixty-eight courses by Howard Benedikt, DC, DCBCN — organizes into three working lanes: the gut, the brain, and the conditions you already treat. Nutrition 201–210 is the foundation block, 211–220 the second, 221–230 the third, 231–240 the fourth, 241–250 the fifth, and 201–224 together form the 48-hour Clinical Nutrition Certification (CNC). Two hours each.
1 · Gut, Microbiome, Digestion and Detoxification
Where nutrient status is decided and where systemic inflammation is won or lost — from the intro principles of micronutrients and absorption to the microbiome, the liver’s biotransformation pathways, the GI disease files, the gut/brain connection, functional GI testing, and digestive enzymes.
201: Introduction to Clinical Nutrition
205: Detoxification
207: Microbiota & the Musculoskeletal System
208: Detoxification II
213: Gastrointestinal Disease & Nutrition
214: An Integrative Approach to Gastrointestinal Disease II
221: The Gut/Brain Connection
225: Functional Medicine Testing for GI Disturbances
248: Maximizing Health Through Proper Digestion and Absorption
258: Oxidative Stress Detoxification — Better Responses to Chiropractic Care
2 · Brain, Mood, Stress and the Nervous System
Nutritional neurology — the headache patient, the stress physiology your patients carry through the door, the brain-game files on how food drives cognition, the nutrition-and-mood pair, the fatigued patient, memory and dementia, nervous-system function, chronic fatigue with myofascial pain, the concussion protocol, the maladaptive stress response, and the fatigue work-up.
203: Nutritional Management of Headaches
204: Chiropractic Nutrition for Stress Management
211: The Brain Game — How Nutrition Impacts Brain Function
212: The Brain Game II — How Food Impacts Brain Function
218: Nutrition and Mood
219: Nutrition and Mood II
228: Dealing with Fatigue in Clinical Practice
233: Memory, Dementia, and Chiropractic Care
234: Optimal Nervous System Function & Nutrition
237: Chronic Fatigue and Myofascial Pain Syndrome — an Integrative Approach
240: Nutritional Management of Concussions in a Clinical Setting
242: Maladaptive Stress Response & Musculoskeletal Disease
244: Managing the Fatigued Patient
247: Optimizing Nervous System Function with Nutrition
251: Autonomic Nervous System Regulation
253: Stress Management II
254: Stress I — How Managing Stress Leads to Better Patient Outcomes
263: Stress Update — Supporting Our Patients During Uncertain Times
264: Brain Game III — How Food Impacts Brain Function
3 · Musculoskeletal, Immune, Hormonal and Clinical Conditions
Nutritional management layered onto what you already treat — arthritic and autoimmune joints, neuropathy and neuropathic pain, immune resilience and the cold-and-flu season, lipids and cholesterol, antioxidants, endocrine disruptors, the thyroid and hormone-testing files, menopause and estrogen, vitamin D, sports injuries, diet and chronic disease, women’s musculoskeletal health, the pain files, the pediatric pair, osteoporosis, and the commonly seen conditions. You are here: Nutrition 216.
202: Nutritional Management of Arthritic Disease
206: Management of Neuropathy
209: Nutrition & the Immune System
210: The Fat Story & Cholesterol
215: Antioxidants in Health and Disease
216: Antioxidants in Health and Disease II
217: Endocrine Disruptors in Health & Disease
220: Management of Autoimmune Disorders — Rheumatoid Arthritis
222: Assessing Thyroid Health in Clinical Practice I
223: Assessing Hormones in Clinical Practice I
224: Assessing Hormones in Clinical Practice II
226: Women’s Health Issues — Focus on Menopause and Estrogen
227: Vitamin D & Musculoskeletal Health
229: Nutritional Management of Sports Injuries
230: A Primer on the Role of Diet and Chronic Disease
231: Women’s Health Issues and the Musculoskeletal System
232: An Integrative Approach to the Musculoskeletal System
235: Pediatric Nutrition & Chiropractic I
236: Pediatric Nutrition & Chiropractic II
238: Chiropractic and Osteoporosis
239: Treating Commonly Seen Conditions in Chiropractic Practice
241: Strengthen Your Immune and Musculoskeletal System through Nutrition and Chiropractic
243: Joint Pain & Inflammation
245: Natural Remedies for the Pain Patient
246: Keeping Healthy During Cold and Flu Season
249: New Strategies for Pain Management in the Chiropractic Setting
250: Neuropathic Pain Management
252: Special Topics in Nutrition
255: Autoimmune Disease II
256: Sports Injury Management in a Chiropractic Office
257: Bone Health
259: Path to Wellness
260: Nutrition and Musculoskeletal Health
261: Wellness and Chiropractic
262: Women’s Health and Nutrition
265: Neuropathy — Pathophysiology and Therapeutic Approaches
266: Comprehensive Approach for Treatment of Joints, Tendons and Ligaments
267: How Nutrition and Chiropractic Go Hand in Hand
269: Nutritional Management of Neuropathy
Every course in the series is 2 PACE-approved CE hours at $40, and the automatic bundle discounts apply across the whole lane. The full 68-course catalog continues on the Nutrition category page.
What You’ll Learn in Nutrition 216
Understand free-radical pathology at an advanced level and explain oxidative-stress mechanisms beyond introductory concepts.
Discuss the diseases connected to free-radical pathology and apply evidence-based antioxidant interventions to patient care plans.
Explain ROS in advanced cell-physiology signaling pathways — inflammation, cellular repair and apoptosis — and why they must not simply be suppressed.
Describe ROS and gene expression: the redox-sensitive, epigenetic pathways and the therapeutic targets they reveal.
Differentiate antioxidant use in diet versus supplementation and recommend the appropriate approach for the individual patient.
Recognize the dangers of indiscriminate supplementation — pro-oxidant effects, blunted immune and exercise adaptation, masked disease, medication interactions — and counsel patients on safe usage thresholds.
Your Nutrition Faculty
Howard Benedikt, DC, DCBCN — instructor of this course. Board-certified chiropractic clinical nutritionist, Diplomate and President of the Chiropractic Board of Clinical Nutrition, with more than 30 years in clinical nutrition and functional medicine. He authors all 68 courses in the CCEDseminars Nutrition library and the Clinical Nutrition Certification (CNC) track at its core, and is known for translating complex nutritional biochemistry into practical, office-ready protocols — here, ROS signaling, gene expression and the antioxidant protocols built on them.
Full bio and the complete instructor roster: CCEDseminars faculty page.
Where Nutrition CE Hours Count — State Rules Worth Knowing
Nutrition coursework is clinical subject matter — assessment, clinical reasoning and nutritional management of patient conditions — which is exactly what several state boards ask for. In Iowa, these hours serve the 36-hour clinical case-management minimum; in Rhode Island, they address the 50-of-60 clinical requirement; and in Vermont — where practice-building coursework earns nothing — patient-care education like this counts fully under the clinical-focus rule.
Online-format allowances still vary by state — some accept every hour online, others cap distance learning or require in-person blocks. Check your state’s guide in the full state directory before building your renewal plan.
Build Your Nutrition Block — or Take the Credential
Every course in the Nutrition series runs 2 hours at $40, so the automatic discounts do the bundling for you: 6–9 hours in one order earns 10% off, and 10 or more earns 20% off — any ten courses from the series is 20 hours, which clears the 20% tier at roughly $320 instead of $400, with no promo codes. Antioxidants II pairs naturally with Nutrition 215, its foundation, and Nutrition 208 on Phase II detoxification and glutathione; the three together reach 6 hours and the 10% tier. Pursuing the credential? The Clinical Nutrition Certification (CNC) packages Nutrition 201–224 — 48 hours — in a single $960 checkout. Browse Nutrition Courses
Nutrition 216 — Frequently Asked Questions
What does Nutrition 216 cover?
Nutrition 216 covers advanced antioxidant science for chiropractors: antioxidants in health and in disease, ROS in advanced cell-physiology signaling, ROS and gene expression with its epigenetic and therapeutic implications, disease-specific antioxidant interventions, diet versus supplementation for the individual patient, and the dangers of indiscriminate supplementation. Also known as ROS and gene expression, advanced oxidative stress nutrition, or antioxidant protocols.
How does Nutrition 216 differ from Nutrition 215?
Nutrition 215 establishes the foundational science of free-radical pathology, oxidative stress and antioxidant categories. Nutrition 216 advances into ROS–gene interactions, disease-specific antioxidant protocols and the clinical dangers of indiscriminate supplementation — the essential follow-up for practitioners who want to apply antioxidant science at the patient level.
How do you reduce oxidative stress safely?
Not by flooding the system with antioxidants. Because ROS also carry the signals for immune function, cellular repair and exercise adaptation, the course teaches evidence-based dosing — food-first strategies, targeted supplementation for the disease in front of you, and the thresholds beyond which supplementation becomes pro-oxidant or masks disease.
What is the clinical significance of ROS and gene expression for chiropractors?
Reactive oxygen species influence gene transcription through redox-sensitive pathways that regulate inflammation, cellular repair and apoptosis. Understanding ROS–gene interactions lets chiropractors identify patients with elevated oxidative burden, explain why lifestyle and dietary choices drive chronic disease risk, and recommend targeted antioxidant interventions grounded in biochemical evidence.
How many CE hours is it, and where does it sit in the Nutrition series?
It is 2 PACE-approved CE hours. Nutrition 216 sits in the musculoskeletal, immune, hormonal and clinical-conditions lane of the Nutrition series with Dr. Howard Benedikt, alongside Nutrition 202, 206, 209, 210, 215, 217 and 220, and is a core module of the Clinical Nutrition Certification.
State Approval and Licensing Reminder
Continuing education requirements — including online-hour caps and clinical-hour minimums — vary by jurisdiction. Review the online chiropractic CE guidelines page and contact CCEDseminars with questions about your specific licensing requirements before registering.
Ready to Enroll in Nutrition 216?
The antioxidant question is a signaling question. Two hours here give you the ROS-to-gene science and the disease-specific protocols to apply it at the patient level — safely.
CCEDseminars · PACE Provider #34015544 · Reviewed by Monte Horne, DC · Last updated September 2026 (CT)